Alphabetical Scientific References for Unlocking Longevity, Healthspan, and Vitality
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Balasubramanian P, Howell PR, Anderson RM. Aging and caloric restriction research: a biological perspective with translational potential. EBioMedicine. 2017;21:37-44. doi: 10.1016/j.ebiom.2017.06.015. PMID: 28666535; PMCID: PMC5544561.
Barja G. Mitochondrial free radicals and aging. Trends in Neurosciences. 2004;27(10):595-600. doi: 10.1016/j.tins.2004.07.005. PMID: 15374670.
Bauer J, Biolo G, Cederholm T, et al. Evidence-based recommendations for optimal dietary protein intake in older people. Clin Nutr. 2013;32(6):929-936. doi: 10.1016/j.clnu.2013.04.018. PMID: 23786752.
Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006;444(7117):337-342. doi: 10.1038/nature05354. PMID: 17086191.
Belsky DW, Caspi A, Arseneault L, et al. Quantification of biological aging in young adults. Proc Natl Acad Sci U S A. 2015;112(30):E4104-E4110. doi: 10.1073/pnas.1506264112. PMID: 26150497; PMCID: PMC4522786.
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Beydoun MA, Beydoun HA, Wang Y. Obesity and central obesity as risk factors for incident dementia and its subtypes. Psychosom Med. 2008;70(3):346-353. doi: 10.1097/PSY.0b013e318165bee2. PMID: 18378874.
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Boeing H, Bechthold A, Bub A, et al. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr. 2012;51(6):637-663. doi: 10.1007/s00394-012-0380-y. PMID: 22684631.
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Brenner C, Boileau RM. Nucleotide excision repair genes and aging. Cell Mol Life Sci. 2020;77(7):1287-1300. doi: 10.1007/s00018-019-03326-3. PMID: 31925530.
Burdge GC, Lillycrop KA. Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease. Annu Rev Nutr. 2010;30:315-339. doi: 10.1146/annurev.nutr.012809.104751. PMID: 20645850.
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Cahill L. Why sex matters for neuroscience. Nat Rev Neurosci. 2006;7(6):477-484. doi: 10.1038/nrn1909. PMID: 16688123.
Calder PC. Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochem Soc Trans. 2017;45(5):1105-1115. doi: 10.1042/BST20160474. PMID: 28900017.
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Cano A, Fortuno A, Quesada A. Endocrine aging and cardiovascular disease. Menopause Int. 2010;16(1):29-33. doi: 10.1258/mi.2009.009047. PMID: 20331801.
Cao L, Chiao M. Molecular pathways: targeting cancer stem cells through reactive oxygen species. Clin Cancer Res. 2014;20(3):584-590. doi: 10.1158/1078-0432.CCR-13-0915. PMID: 23975884.
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Carvalho C, Moreira PI. Oxidative stress: a major player in cerebrovascular alterations associated to neurodegenerative events. Front Physiol. 2018;9:806. doi: 10.3389/fphys.2018.00806. PMID: 29977276; PMCID: PMC6019295.
Castro JP, Jung T, Grune T, Siems W. 80 years of research on protein oxidation: from the identification of oxidized proteins to proteomic approaches in aging research. Arch Biochem Biophys. 2013;542:3-11. doi: 10.1016/j.abb.2013.01.021. PMID: 23380396.
Chan DC, McKenzie B, Colman G, Boushey CJ. Importance of vitamin D status and lifestyle factors on bone mineral density in older adults. J Nutr Health Aging. 2011;15(7):535-541. doi: 10.1007/s12603-011-0034-2. PMID: 21849637.
Chen R, Ovbiagele B, Feng W. Diabetes and stroke: epidemiology, pathophysiology, pharmaceuticals and outcomes. Am J Med Sci. 2016;351(4):380-386. doi: 10.1016/j.amjms.2016.01.011. PMID: 27079344; PMCID: PMC4932700.
Cheng HL, Medlow S, Steinbeck K. The health consequences of obesity in young adulthood. Curr Obes Rep. 2016;5(1):30-37. doi: 10.1007/s13679-016-0197-7. PMID: 26769885.
Chowdhury R, Stevens S, Gorman D, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ. 2014;348:g1903. doi: 10.1136/bmj.g1903. PMID: 24690623; PMCID: PMC3972410.
Chrousos GP. Stress and disorders of the stress system. Nat Rev Endocrinol. 2009;5(7):374-381. doi: 10.1038/nrendo.2009.106. PMID: 19488073.
Cohen HY, Miller C, Bitterman KJ, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science. 2004;305(5682):390-392. doi: 10.1126/science.1099196. PMID: 15205477.
Corder R, Douthwaite JA, Lees DM, et al. Endothelin-1 synthesis reduced by red wine polyphenols: implications for health. Nature. 2001;414(6866):863-864. doi: 10.1038/414863a. PMID: 11780056.
Corpas E, Harman SM, Blackman MR. Human growth hormone and human aging. Endocr Rev. 1993;14(1):20-39. doi: 10.1210/edrv-14-1-20. PMID: 8484342.
Costello LC, Franklin RB. Zinc is decreased in prostate cancer: an established relationship of prostate cancer! J Biol Inorg Chem. 2006;11(7):943-957. doi: 10.1007/s00775-006-0142-6. PMID: 16909251.
Cotman CW, Berchtold NC. Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci. 2002;25(6):295-301. doi: 10.1016/s0166-2236(02)02143-4. PMID: 12086747.
Cunnane SC, Courchesne-Loyer A, Vandenberghe C, et al. Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer’s disease. Ann N Y Acad Sci. 2016;1367(1):12-20. doi: 10.1111/nyas.12999. PMID: 26766547.
Dahl WJ, Stewart ML. Position of the Academy of Nutrition and Dietetics: Health implications of dietary fiber. J Acad Nutr Diet. 2015;115(11):1861-1870. doi: 10.1016/j.jand.2015.09.003. PMID: 26514720.
de Cabo R, Mattson MP. Effects of intermittent fasting on health, aging, and disease. N Engl J Med. 2019;381(26):2541-2551. doi: 10.1056/NEJMra1905136. PMID: 31881139; PMCID: PMC7285169.
de la Monte SM, Wands JR. Alzheimer’s disease is type 3 diabetes–evidence reviewed. J Diabetes Sci Technol. 2008;2(6):1101-1113. doi: 10.1177/193229680800200619. PMID: 19885293; PMCID: PMC2769828.
Després JP. Body fat distribution and risk of cardiovascular disease: an update. Circulation. 2012;126(10):1301-1313. doi: 10.1161/CIRCULATIONAHA.111.067264. PMID: 22949540.
Diekelmann S, Born J. The memory function of sleep. Nat Rev Neurosci. 2010;11(2):114-126. doi: 10.1038/nrn2762. PMID: 20046194.
Dinan TG, Cryan JF. The microbiome-gut-brain axis in health and disease. Gastroenterol Clin North Am. 2017;46(1):77-89. doi: 10.1016/j.gtc.2016.09.007. PMID: 28164855.
Elamin MH, Shinwari Z, Hendawi M. NAD+ and its precursors in aging and age-related diseases. GeroScience. 2021;43(3):1021-1034. doi: 10.1007/s11357-020-00300-2. PMID: 33043389.
Eliassen AH, Colditz GA, Rosner B, Willett WC, Hankinson SE. Adult weight change and risk of postmenopausal breast cancer. JAMA. 2006;296(2):193-201. doi: 10.1001/jama.296.2.193. PMID: 16835423.
Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279-1290. doi: 10.1056/NEJMoa1200303. PMID: 23432189.
Ferguson G, Sheldon J. Cardiovascular risk and cholesterol management: new perspectives. Br J Gen Pract. 2014;64(620):610-611. doi: 10.3399/bjgp14X682633. PMID: 25548311; PMCID: PMC4240093.
Fink HA, Ginsberg TB. Cardiovascular disease and osteoporosis: balancing treatment benefits and risks. J Gerontol A Biol Sci Med Sci. 2006;61(4):362-371. doi: 10.1093/gerona/61.4.362. PMID: 16611704.
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature. 2000;408(6809):239-247. doi: 10.1038/35041687. PMID: 11089981.
Fontana L, Partridge L. Promoting health and longevity through diet: From model organisms to humans. Cell. 2015;161(1):106-118. doi: 10.1016/j.cell.2015.02.020. PMID: 25815990.
Franceschi C, Garagnani P, Parini P, Giuliani C, Santoro A. Inflammaging: a new immune–metabolic viewpoint for age-related diseases. Nat Rev Endocrinol. 2018;14(10):576-590. doi: 10.1038/s41574-018-0059-4. PMID: 30065258.
Franklin SS, Wong ND. Hypertension and cardiovascular disease: contributions of the Framingham Heart Study. Glob Heart. 2013;8(1):49-57. doi: 10.1016/j.gheart.2012.12.004. PMID: 25690304.
Freitas AA, de Magalhães JP. A review and appraisal of the DNA damage theory of ageing. Mutat Res. 2011;728(1-2):12-22. doi: 10.1016/j.mrfmmm.2011.07.010. PMID: 21840364.
Friedman J, Nunnari J. Mitochondrial form and function. Nature. 2014;505(7483):335-343. doi: 10.1038/nature12985. PMID: 24429632.
Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340(6):448-454. doi: 10.1056/NEJM199902113400607. PMID: 9971870.
Godos J, Ferri R, Caraci F, et al. Adherence to the Mediterranean diet is associated with better sleep quality in Italian adults. Nutrients. 2019;11(5):976. doi: 10.3390/nu11050976. PMID: 31060394; PMCID: PMC6566614.
Gomez-Pinilla F. Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci. 2008;9(7):568-578. doi: 10.1038/nrn2421. PMID: 18568016.
Grant WB. Using multicountry ecological and observational studies to determine dietary risk factors for Alzheimer’s disease. J Am Coll Nutr. 2016;35(5):476-489. doi: 10.1080/07315724.2015.1080127. PMID: 26880680.
Guarente L. Sirtuins, aging, and medicine. N Engl J Med. 2011;364(23):2235-2244. doi: 10.1056/NEJMra1100831. PMID: 21651395.
Gustafson DR. Adiposity hormones and dementia. J Neurol Sci. 2010;299(1-2):30-34. doi: 10.1016/j.jns.2010.08.004. PMID: 20800929.
Halliwell B. Free radicals and antioxidants: updating a personal view. Nutr Rev. 2012;70(5):257-265. doi: 10.1111/j.1753-4887.2012.00476.x. PMID: 22537212.
Hanage WP. Microbiology: Microbiome science needs a healthy dose of scepticism. Nature. 2014;512(7514):247-248. doi: 10.1038/512247a. PMID: 25119291.
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11(3):298-300. doi: 10.1093/geronj/11.3.298. PMID: 13332224.
Haus JM, Carrithers JA, Trappe SW, Trappe TA. Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle. J Appl Physiol (1985). 2007;103(6):2068-2076. doi: 10.1152/japplphysiol.00670.2007. PMID: 17901242.
Hooshmand B, Solomon A, Kåreholt I, et al. Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal population-based study. Am J Clin Nutr. 2010;92(3):595-603. doi: 10.3945/ajcn.2010.29482. PMID: 20685947.
Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14(10):R115. doi: 10.1186/gb-2013-14-10-r115. PMID: 24138928; PMCID: PMC4015143.
Houston DK, Nicklas BJ, Ding J, et al. Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr. 2008;87(1):150-155. doi: 10.1093/ajcn/87.1.150. PMID: 18175749.
Hu FB, Willett WC. Optimal diets for prevention of coronary heart disease. JAMA. 2002;288(20):2569-2578. doi: 10.1001/jama.288.20.2569. PMID: 12444864.
Hyman M, Malek M. The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First. Scribner; 2008.
Jeong SM, Choi S, Kim K, Kim SM, Lee G, Park SM. Effect of change in total cholesterol levels on cardiovascular disease among young adults. J Am Heart Assoc. 2018;7(12):e008819. doi: 10.1161/JAHA.118.008819. PMID: 29910199; PMCID: PMC6064851.
Kaeberlein M. The biology of aging: citizen scientists and their pets as a bridge between research on model organisms and human subjects. Vet Pathol. 2016;53(2):291-298. doi: 10.1177/0300985815591082. PMID: 26136707; PMCID: PMC4779180.
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Kiecolt-Glaser JK, McGuire L, Robles TF, Glaser R. Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology. Annu Rev Psychol. 2002;53:83-107. doi: 10.1146/annurev.psych.53.100901.135217. PMID: 11752482.
Kivipelto M, Ngandu T, Fratiglioni L, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol. 2005;62(10):1556-1560. doi: 10.1001/archneur.62.10.1556. PMID: 16216938.
Knight JA. Review: Free radicals, antioxidants, and the immune system. Ann Clin Lab Sci. 2000;30(2):145-158. PMID: 10800390.
Kong F, Lin K. Oxidative stress in cancer: a double-edged sword. Cancer Lett. 2010;289(2):174-185. doi: 10.1016/j.canlet.2009.08.016. PMID: 19716385.
Koyama A, O’Brien J, Weuve J, et al. The role of peripheral inflammatory markers in dementia and Alzheimer’s disease: a meta-analysis. J Gerontol A Biol Sci Med Sci. 2013;68(4):433-440. doi: 10.1093/gerona/gls187. PMID: 22982688.
Lang PO, Samaras D, Samaras N, Aspinall R. How important is nutrition in adult neurogenesis? Clin Interv Aging. 2010;5:187-200. doi: 10.2147/CIA.S9956. PMID: 20628630; PMCID: PMC2907136.
Larsson SC, Orsini N, Wolk A. Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies. JAMA. 2010;303(11):1077-1083. doi: 10.1001/jama.2010.263. PMID: 20233823.
Le Couteur DG, Solon-Biet S, Cogger VC, Mitchell SJ, Senior A, de Cabo R, Simpson SJ. The impact of low-protein high-carbohydrate diets on aging and lifespan. Cell Mol Life Sci. 2016;73(6):1237-1252. doi: 10.1007/s00018-015-2112-4. PMID: 26538595.
Lichtenstein AH, Appel LJ, Brands M, et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the AHA Nutrition Committee. Circulation. 2006;114(1):82-96. doi: 10.1161/CIRCULATIONAHA.106.176158. PMID: 16785338.
Longo VD, Panda S. Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan. Cell Metab. 2016;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC4924195.
Lourida I, Hannon E, Littlejohns TJ, et al. Association of lifestyle and genetic risk with incidence of dementia. JAMA. 2019;322(5):430-437. doi: 10.1001/jama.2019.9879. PMID: 31310296; PMCID: PMC6687260.
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-1217. doi: 10.1016/j.cell.2013.05.039. PMID: 23746838.
Maher P. The potential of flavonoids for the treatment of neurodegenerative diseases. Int J Mol Sci. 2019;20(12):3056. doi: 10.3390/ijms20123056. PMID: 31234355; PMCID: PMC6617157.
Mann N, Skeaff CM. Lipids and health: an update. Nutrients. 2016;8(5):312. doi: 10.3390/nu8050312. PMID: 27187435; PMCID: PMC4882689.
Mattson MP. Energy intake and exercise as determinants of brain health and vulnerability to injury and disease. Cell Metab. 2012;16(6):706-722. doi: 10.1016/j.cmet.2012.11.008. PMID: 23217265.
McEwen BS. Protective and damaging effects of stress mediators: central role of the brain. Dialogues Clin Neurosci. 2006;8(4):367-381. PMID: 17290796; PMCID: PMC3181832.
Miller AH, Raison CL. The role of inflammation in depression: from evolutionary imperative to modern treatment target. Nat Rev Immunol. 2016;16(1):22-34. doi: 10.1038/nri.2015.5. PMID: 26711676.
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Mozaffarian D, Micha R, Wallace S. Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2010;7(3):e1000252. doi: 10.1371/journal.pmed.1000252. PMID: 20351774; PMCID: PMC2843598.
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Scientific References for Unlocking Longevity, Healthspan, and Vitality
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